Prionex® 10%

Prionex® is a 10% aqueous solution of a polypeptide fraction of highly purified dermal collagen of porcine origin which has excellent protein stabilizing properties. Prionex® is prepared by partial hydrolysis and is terminally sterilized. It is free from cartilage, bone and plasma components and is therefore a pure form of partially hydrolyzed gelatine type A. Additionally, Prionex® is free from nucleic acids, polysaccharides and lipids as well as any additives.

APPLICATION:
Prionex® can be used advantageously to optimize the stability of biological activity; improve conditions for lyophilisation and heat treatment; eliminate the use of bovine-derived materials; prevent denaturation by chaotropic agents or solvents; and to extend the shelf life of enzymes and proteins. Additionally, Prionex® is additive free and can serve as a high consistency stabilizer.

Prionex® is a proven stabilizer for in-vitro diagnostic (IVD) applications:
• Protein stabilization
• Preservation of biological activity
• Adsorption prevention
• Shelf-life extension
• Lyophilization and heat treatment excipient
• Blocking agent in immunoassays to reduce non-specific binding

ADVANTAGES
Prionex® is freely soluble in water, diluted electrolyte solutions, glycerol and DMSO as well as in diluted ethanol and ammonium sulphate solutions below 20% saturation.

It can be used beneficially to:
• Optimize the stability of biological activity
• Improve conditions for lyophilisation and heat treatment
• Avoid denaturation by chaotropic agents or solvents
• Extends shelf life for enzymes and proteins
• High consistency stabilizer
• Non-toxic and non-antigenic