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| Biotechnology |
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PENTAPHARM's biotechnological R&D and manufacturing services for fermentation and downstream processing include:
- Process optimization, increase of productivity for recombinant expression of proteins, using microbial expression systems, such as Escherichia coli and yeasts i.e. Saccharomyces cerevisiae and Pichia pastoris
- Fermentation up to the 500 litres
- Purification of inclusion-bodies from E.coli expression systems
- Optimization of protein folding and scale-up
- Biotransformation for customized molecules, including process optimization and manufacturing
- Large-scale purification
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