| |||||||||||||
|
|
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
COAGULATION INHIBITORS/THROMBOHILIA MARKERS
Pefakit® APC-R Factor V Leiden is a plasma based functional assay for the determination of resistance to activated protein C caused by the factor V Leiden mutation (FV:Q506). It is a plasma-based functional clotting assay and differs from other functional APC resistance tests by acting specifically on the prothrombinase complex level. It is based on a FV-dependent prothrombin activator isolated from snake venom. Robustness and specificity of the assay is enhanced by elimination of possible disturbing influences by factors upstream the coagulation cascade and independency from calcium. Interference from UFH, LMWH and Pentasaccharide in the blood sample is precluded by a heparin inhibitor. Features · Funcional clotting assay with unparalleled specificity and sensitivity · Not influenced by Lupus anticoagulants, proetein C, protein S, Heparins, AT, Fibrinogen and abnormal conditions of PT, FVIII, FX, TFPI and D-Dimer · PCR-like results Pefakit® APC-R Factor V Leiden Controls
Control plasmas for confirmation of factor V Leiden mutation (FV:Q506) in assays for determination of the functional phenotype for activated protein C resistance caused by the factor V Leiden mutation. |